Summary

• Fast-spiking inhibitory interneurons: 500 - 700 Hz
• Rat Layer 5 Pyramidal Neurons (Schwindt et al., 1997):
• Minimum Steady Firing Rate: 10 $\pm$ 0.4 Hz (5 - 16 Hz)
• Maximum Steady Firing Rate: 74 Hz (6.7 $\pm$ 0.4 x minimum rate)

Primary Sources

• Azouz, R., Gray, C. M., Nowak, L. G., and McCormick, D. A. (1997). Physiological properties of inhibitory interneurons in cat striate cortex. Cereb. Cortex, 7, 534–545.
• Schwindt, P., O'Brien, J.A., and Crill, W. (1997). Quantitative Analysis of Firing Properties of Pyramidal Neurons From Layer 5 of Rat Sensorimotor Cortex. J. Neurophysiol., 77, 2484-2498.

Secondary Sources

• Parisien, C., Anderson, C.H., Eliasmith, C. (2008). Solving the problem of negative synaptic weights in cortical models. Neural Computation. 20, 1473-1494.

The parameters for the LIF neuron models are as follows: membrane time constant τ RC = 10 ms; refractory period τref = 1 ms; peak firing rates over the represented range are chosen from a uniform distribution over 200 to 400 Hz. Inhibitory interneurons are similarly modeled, except that their firing saturates at a higher rate: between 500 and 700 Hz (Azouz et al., 1997).