Modeling brain function: Current developments and future prospects

JAMA Neurology, 2013

Daniel Rasmussen, Chris Eliasmith

Abstract

We discuss work aimed at building functional models of the whole brain implemented in large-scale simulations of millions of individual neurons. Recent developments in this area demonstrate that such models can explain a variety of behavioral, neurophysiological, and neuroanatomical data. We argue that these models hold the potential to expand our understanding of the brain by connecting these levels of analysis in new and informative ways. However, current modeling efforts fall short of the target of whole-brain modeling. Consequently, we discuss different avenues of research that continue to progress toward that distant, but achievable, goal.

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Doi
10.1001/jamaneurol.2013.3835
Issn
2168-6157
Journal
JAMA Neurology
Number
10
Pages
1325–1329
Pmid
23978906
Volume
70

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